Learn. Mem.
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     

Published online before print November 13, 2006, 10.1101/lm.317806
LEARNING & MEMORY 13:686-689
©2006 by Cold Spring Harbor Laboratory Press; ISSN 1072-0502/06 $5.00
This Article
Right arrow Full Text
Right arrow Full Text (PDF)
Right arrow All Versions of this Article:
lm.317806v1
13/6/686    most recent
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Right arrow Citation Map
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrow reprints & permissions
Citing Articles
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Mehren, J. E.
Right arrow Articles by Griffith, L. C.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Mehren, J. E.
Right arrow Articles by Griffith, L. C.
Social Bookmarking
Add to CiteULike   Add to Connotea   Add to Del.icio.us   Add to Digg   Add to Reddit   Add to Technorati  
What's this?

Brief Communication
Cholinergic neurons mediate CaMKII-dependent enhancement of courtship suppression

Jennifer E. Mehren1 and Leslie C. Griffith2

Brandeis University, Department of Biology and Volen Center for Complex Systems, Waltham, Massachusetts 02454-9110, USA

In Drosophila, calcium/calmodulin-dependent protein kinase II (CaMKII) activity is crucial in associative courtship conditioning for both memory formation and suppression of courtship during training with a mated female. We have previously shown that increasing levels of constitutively active CaMKII, but not calcium-dependent CaMKII, in a subset of neurons can decrease the initial level of courtship and enhance the rate of suppression of courtship in response to a mated female. In this study, we demonstrate that a subpopulation of noncholinergic, nondopaminergic, non-GABAergic neurons can cause CaMKII-dependent reductions in initial courtship, but only cholinergic neurons enhance training-dependent suppression. These data suggest that processing of pheromonal signals in two subpopulations of neurons, likely antennal lobe projection neurons, is critical for behavioral plasticity.

Received May 11, 2006; accepted in revised form July 18, 2006.

2 Corresponding author.

E-mail griffith{at}brandeis.edu; fax (781) 736-3107.

1 Present address: Laboratory of Neurogenetics and Behavior, The Rockefeller University, New York, New York 10021-6399, USA.

Article published online before print. Article and publication date are at http://www.learnmem.org/cgi/doi/10.1101/lm.317806


Add to CiteULike CiteULike   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us   Add to Digg Digg   Add to Reddit Reddit   Add to Technorati Technorati    What's this?




HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
Copyright © 2006 by the Cold Spring Harbor Laboratory Press.