HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS		QUICK SEARCH:   [advanced] Author: Keyword(s): Year:  Vol:  Page:

This Article Full Text Full Text (PDF) Alert me when this article is cited Alert me if a correction is posted Citation Map Services Email this article to a friend Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Citing Articles Citing Articles via HighWire Citing Articles via Google Scholar Google Scholar Articles by Crow, T. Search for Related Content PubMed PubMed Citation Articles by Crow, T. Social Bookmarking                   What's this?

Review
Pavlovian Conditioning of Hermissenda: Current Cellular, Molecular, and Circuit Perspectives

Terry Crow

Department of Neurobiology and Anatomy, University of Texas Medical School, Houston, Texas 77030, USA

ABSTRACT

The less-complex central nervous system of many invertebrates make them attractive for not only the molecular analysis of the associative learning and memory, but also in determining how neural circuits are modified by learning to generate changes in behavior. The nudibranch mollusk Hermissenda crassicornis is a preparation that has contributed to an understanding of cellular and molecular mechanisms of Pavlovian conditioning. Identified neurons in the conditioned stimulus (CS) pathway have been studied in detail using biophysical, biochemical, and molecular techniques. These studies have resulted in the identification and characterization of specific membrane conductances contributing to enhanced excitability and synaptic facilitation in the CS pathway of conditioned animals. Second-messenger systems activated by the CS and US have been examined, and proteins that are regulated by one-trial and multi-trial Pavlovian conditioning have been identified in the CS pathway. The recent progress that has been made in the identification of the neural circuitry supporting the unconditioned response (UR) and conditioned response (CR) now provides for the opportunity to understand how Pavlovian conditioning is expressed in behavior.

E-MAIL terry.crow{at}uth.tmc.edu; FAX (713) 500-0623.

CiteULike    Connotea    Del.icio.us    Digg    Reddit    Technorati    What's this?

This article has been cited by other articles:

				R. Crook and J. Basil A biphasic memory curve in the chambered nautilus, Nautilus pompilius L. (Cephalopoda: Nautiloidea) J. Exp. Biol., June 15, 2008; 211(12): 1992 - 1998. [Abstract] [Full Text] [PDF]

				D. A. Baxter and J. H. Byrne Feeding behavior of Aplysia: A model system for comparing cellular mechanisms of classical and operant conditioning Learn. Mem., November 1, 2006; 13(6): 669 - 680. [Abstract] [Full Text] [PDF]

				L.-M. Tian, R. Kawai, and T. Crow Serotonin-Immunoreactive CPT Interneurons in Hermissenda: Identification of Sensory Input and Motor Projections J Neurophysiol, July 1, 2006; 96(1): 327 - 335. [Abstract] [Full Text] [PDF]

				A. M. Kuzirian, H. T. Epstein, C. J. Gagliardi, T. J. Nelson, M. Sakakibara, C. Taylor, A. B. Scioletti, and D. L. Alkon Bryostatin Enhancement of Memory in Hermissenda Biol. Bull., June 1, 2006; 210(3): 201 - 214. [Abstract] [Full Text] [PDF]

				T. Crow and L.-M. Tian Pavlovian Conditioning in Hermissenda: A Circuit Analysis Biol. Bull., June 1, 2006; 210(3): 289 - 297. [Abstract] [Full Text] [PDF]

				V. A. Straub, I. Kemenes, M. O'Shea, and P. R. Benjamin Associative Memory Stored by Functional Novel Pathway rather than Modifications of Preexisting Neuronal Pathways J. Neurosci., April 12, 2006; 26(15): 4139 - 4146. [Abstract] [Full Text] [PDF]

				R. D. Hawkins, G. A. Clark, and E. R. Kandel Operant Conditioning of Gill Withdrawal in Aplysia J. Neurosci., March 1, 2006; 26(9): 2443 - 2448. [Abstract] [Full Text] [PDF]

				V. Agin, R. Chichery, L. Dickel, and M.-P. Chichery The "prawn-in-the-tube" procedure in the cuttlefish: Habituation or passive avoidance learning? Learn. Mem., January 1, 2006; 13(1): 97 - 101. [Abstract] [Full Text] [PDF]